The type 1 insulin-like growth factor receptor pathway

Research conducted over the past two decades has shown the importance of the type 1 insulin-like growth factor receptor (IGF1R) in tumorigenesis, metastasis, and resistance to existing forms of cancer therapy. The IGF1R itself has only recently been accepted as a credible treatment target, however,...

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Vydané v:	Clinical cancer research Ročník 14; číslo 20; s. 6364
Hlavní autori:	Chitnis, Meenali M, Yuen, John S P, Protheroe, Andrew S, Pollak, Michael, Macaulay, Valentine M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 15.10.2008
Predmet:	Animals Antineoplastic Agents - therapeutic use Humans Neoplasms - drug therapy Receptor, IGF Type 1 - antagonists & inhibitors Receptor, IGF Type 1 - physiology Receptor, Insulin - physiology Signal Transduction - drug effects
ISSN:	1078-0432
On-line prístup:	Zistit podrobnosti o prístupe
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