Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing

Diffuse large B-cell lymphoma (DLBCL) is a genetically heterogeneous cancer composed of at least 2 molecular subtypes that differ in gene expression and distribution of mutations. Recently, application of genome/exome sequencing and RNA-seq to DLBCL has revealed numerous genes that are recurrent tar...

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Veröffentlicht in:	Blood Jg. 122; H. 7; S. 1256
Hauptverfasser:	Morin, Ryan D, Mungall, Karen, Pleasance, Erin, Mungall, Andrew J, Goya, Rodrigo, Huff, Ryan D, Scott, David W, Ding, Jiarui, Roth, Andrew, Chiu, Readman, Corbett, Richard D, Chan, Fong Chun, Mendez-Lago, Maria, Trinh, Diane L, Bolger-Munro, Madison, Taylor, Greg, Hadj Khodabakhshi, Alireza, Ben-Neriah, Susana, Pon, Julia, Meissner, Barbara, Woolcock, Bruce, Farnoud, Noushin, Rogic, Sanja, Lim, Emilia L, Johnson, Nathalie A, Shah, Sohrab, Jones, Steven, Steidl, Christian, Holt, Robert, Birol, Inanc, Moore, Richard, Connors, Joseph M, Gascoyne, Randy D, Marra, Marco A
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 15.08.2013
Schlagworte:	Biomarkers, Tumor - chemistry Biomarkers, Tumor - genetics DNA Copy Number Variations - genetics Gene Expression Profiling Genome, Human GTP-Binding Protein alpha Subunits, G12-G13 - chemistry GTP-Binding Protein alpha Subunits, G12-G13 - genetics High-Throughput Nucleotide Sequencing Humans Lymphoma, Large B-Cell, Diffuse - genetics Mutation - genetics Oligonucleotide Array Sequence Analysis Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Tumor Cells, Cultured
ISSN:	1528-0020, 1528-0020
Online-Zugang:	Weitere Angaben
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