Backs against the wall: novel and existing strategies used during the 2014-2015 Ebola virus outbreak

The 2014-2015 outbreak of Ebola virus (EBOV), originating from Guinea, is now responsible for the infection of >20,000 people in 9 countries. Whereas past filovirus outbreaks in sub-Saharan Africa have been rapidly brought under control with comparably few cases, this outbreak has been particular...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Clinical microbiology reviews Ročník 28; číslo 3; s. 593
Hlavní autoři: Wong, Gary, Kobinger, Gary P
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 01.07.2015
Témata:
Disease Management
Disease Outbreaks
Drugs, Investigational - therapeutic use
Ebolavirus
Hemorrhagic Fever, Ebola - epidemiology
Hemorrhagic Fever, Ebola - therapy
Humans
Therapies, Investigational
ISSN:1098-6618, 1098-6618
On-line přístup:Zjistit podrobnosti o přístupu
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:The 2014-2015 outbreak of Ebola virus (EBOV), originating from Guinea, is now responsible for the infection of >20,000 people in 9 countries. Whereas past filovirus outbreaks in sub-Saharan Africa have been rapidly brought under control with comparably few cases, this outbreak has been particularly resistant to containment efforts. Both the general population and primary health care workers have been affected by this outbreak, with hundreds of doctors and nurses being infected in the line of duty. In the absence of approved therapeutics, several caregivers have turned to investigational new drugs as well as experimental therapies in an effort to save lives. This review aims to summarize the candidates currently under consideration for postexposure use in infected patients during the largest EBOV outbreak in history.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:1098-6618
1098-6618
DOI:10.1128/CMR.00014-15