Unraveling the web of viroinformatics: computational tools and databases in virus research

The beginning of the second century of research in the field of virology (the first virus was discovered in 1898) was marked by its amalgamation with bioinformatics, resulting in the birth of a new domain--viroinformatics. The availability of more than 100 Web servers and databases embracing all or...

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Bibliographic Details
Published in:Journal of virology Vol. 89; no. 3; p. 1489
Main Authors: Sharma, Deepak, Priyadarshini, Pragya, Vrati, Sudhanshu
Format: Journal Article
Language:English
Published: United States 01.02.2015
Subjects:
Computational Biology - methods
Databases as Topic
Internet
Virology - methods
ISSN:1098-5514, 1098-5514
Online Access:Get more information
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Summary:The beginning of the second century of research in the field of virology (the first virus was discovered in 1898) was marked by its amalgamation with bioinformatics, resulting in the birth of a new domain--viroinformatics. The availability of more than 100 Web servers and databases embracing all or specific viruses (for example, dengue virus, influenza virus, hepatitis virus, human immunodeficiency virus [HIV], hemorrhagic fever virus [HFV], human papillomavirus [HPV], West Nile virus, etc.) as well as distinct applications (comparative/diversity analysis, viral recombination, small interfering RNA [siRNA]/short hairpin RNA [shRNA]/microRNA [miRNA] studies, RNA folding, protein-protein interaction, structural analysis, and phylotyping and genotyping) will definitely aid the development of effective drugs and vaccines. However, information about their access and utility is not available at any single source or on any single platform. Therefore, a compendium of various computational tools and resources dedicated specifically to virology is presented in this article.
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ISSN:1098-5514
1098-5514
DOI:10.1128/JVI.02027-14