Osteopontin impairs host defense during pneumococcal pneumonia

Streptococcus pneumoniae is the most frequently isolated pathogen responsible for community-acquired pneumonia. Osteopontin is involved in inflammation during both innate and adaptive immunity. To determine the role of osteopontin in the host response during pneumococcal pneumonia, osteopontin knock...

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Veröffentlicht in:	The Journal of infectious diseases Jg. 203; H. 12; S. 1850
Hauptverfasser:	van der Windt, Gerritje J W, Hoogendijk, Arie J, Schouten, Marcel, Hommes, Tijmen J, de Vos, Alex F, Florquin, Sandrine, van der Poll, Tom
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 15.06.2011
Schlagworte:	Animals Cytokines - analysis Interleukins - analysis Kaplan-Meier Estimate Lung - microbiology Lung - physiopathology Mice Mice, Inbred C57BL Mice, Knockout Osteopontin - analysis Osteopontin - genetics Osteopontin - immunology Phagocytosis Pneumonia, Pneumococcal - immunology Pneumonia, Pneumococcal - physiopathology Streptococcus pneumoniae - immunology
ISSN:	1537-6613, 1537-6613
Online-Zugang:	Weitere Angaben
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