HLALA—HLA typing from linearly projected graph alignments

Abstract Summary HLA*LA implements a new graph alignment model for human leukocyte antigen (HLA) type inference, based on the projection of linear alignments onto a variation graph. It enables accurate HLA type inference from whole-genome (99% accuracy) and whole-exome (93% accuracy) Illumina data;...

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Vydané v:	Bioinformatics Ročník 35; číslo 21; s. 4394 - 4396
Hlavní autori:	Dilthey, Alexander T, Mentzer, Alexander J, Carapito, Raphael, Cutland, Clare, Cereb, Nezih, Madhi, Shabir A, Rhie, Arang, Koren, Sergey, Bahram, Seiamak, McVean, Gil, Phillippy, Adam M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Oxford University Press 01.11.2019 Oxford University Press (OUP)
Predmet:	Applications Notes Genome High-Throughput Nucleotide Sequencing Histocompatibility Testing Humans Immunology Life Sciences Sequence Analysis, DNA Software
ISSN:	1367-4803, 1367-4811, 1460-2059, 1367-4811
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