HLALA—HLA typing from linearly projected graph alignments

Abstract Summary HLA*LA implements a new graph alignment model for human leukocyte antigen (HLA) type inference, based on the projection of linear alignments onto a variation graph. It enables accurate HLA type inference from whole-genome (99% accuracy) and whole-exome (93% accuracy) Illumina data;...

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Bibliographic Details

Published in:	Bioinformatics Vol. 35; no. 21; pp. 4394 - 4396
Main Authors:	Dilthey, Alexander T, Mentzer, Alexander J, Carapito, Raphael, Cutland, Clare, Cereb, Nezih, Madhi, Shabir A, Rhie, Arang, Koren, Sergey, Bahram, Seiamak, McVean, Gil, Phillippy, Adam M
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01.11.2019 Oxford University Press (OUP)
Subjects:	Applications Notes Genome High-Throughput Nucleotide Sequencing Histocompatibility Testing Humans Immunology Life Sciences Sequence Analysis, DNA Software
ISSN:	1367-4803, 1367-4811, 1460-2059, 1367-4811
Online Access:	Get full text
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