Covid‐19 and the digestive system

The novel coronavirus disease is currently causing a major pandemic. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a member of the Betacoronavirus genus that also includes the SARS‐CoV and Middle East respiratory syndrome coronavirus. While patients typically pres...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	Journal of gastroenterology and hepatology Ročník 35; číslo 5; s. 744 - 748
Hlavní autoři:	Wong, Sunny H, Lui, Rashid NS, Sung, Joseph JY
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Australia Wiley Subscription Services, Inc 01.05.2020
Témata:	ACE2 Aerosols - adverse effects Angiotensin Angiotensin-Converting Enzyme 2 Betacoronavirus - isolation & purification Betacoronavirus - metabolism Coronaviridae coronavirus Coronavirus Infections - complications Coronavirus Infections - diagnosis Coronavirus Infections - metabolism Coronavirus Infections - transmission Coronaviruses COVID-19 Diarrhea Digestive System - cytology Digestive System - metabolism Digestive System - virology Digestive System Diseases - metabolism Digestive System Diseases - virology Disease transmission Disease Transmission, Infectious - prevention & control Epithelial cells Fever gastrointestinal infection Gastrointestinal tract Humans Infection Control - methods Pandemics Peptidyl-dipeptidase A Peptidyl-Dipeptidase A - biosynthesis pneumonia Pneumonia, Viral - complications Pneumonia, Viral - diagnosis Pneumonia, Viral - metabolism Pneumonia, Viral - transmission Ribonucleic acid RNA RNA, Viral - isolation & purification SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Vomiting coronavirus gastrointestinal infection Covid-19 pneumonia diarrhea
ISSN:	0815-9319, 1440-1746, 1440-1746
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Popis
Shrnutí:	The novel coronavirus disease is currently causing a major pandemic. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a member of the Betacoronavirus genus that also includes the SARS‐CoV and Middle East respiratory syndrome coronavirus. While patients typically present with fever and a respiratory illness, some patients also report gastrointestinal symptoms such as diarrhea, vomiting, and abdominal pain. Studies have identified the SARS‐CoV‐2 RNA in stool specimens of infected patients, and its viral receptor angiotensin converting enzyme 2 was found to be highly expressed in gastrointestinal epithelial cells. These suggest that SARS‐CoV‐2 can actively infect and replicate in the gastrointestinal tract. This has important implications to the disease management, transmission, and infection control. In this article, we review the important gastrointestinal aspects of the disease.
Bibliografie:	The authors declare no conflict of interest. Declaration of conflict of interest ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23
ISSN:	0815-9319 1440-1746 1440-1746
DOI:	10.1111/jgh.15047