The Human Skin Double-Stranded DNA Virome: Topographical and Temporal Diversity, Genetic Enrichment, and Dynamic Associations with the Host Microbiome

Viruses make up a major component of the human microbiota but are poorly understood in the skin, our primary barrier to the external environment. Viral communities have the potential to modulate states of cutaneous health and disease. Bacteriophages are known to influence the structure and function...

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Bibliographic Details
Published in:	mBio Vol. 6; no. 5; pp. e01578 - e01515
Main Authors:	Hannigan, Geoffrey D., Meisel, Jacquelyn S., Tyldsley, Amanda S., Zheng, Qi, Hodkinson, Brendan P., SanMiguel, Adam J., Minot, Samuel, Bushman, Frederic D., Grice, Elizabeth A.
Format:	Journal Article
Language:	English
Published:	United States American Society for Microbiology 20.10.2015 American Society of Microbiology
Subjects:	Antibiotic resistance Antibiotics Bacteria - classification Bacteria - genetics Bacteriophages - classification Bacteriophages - genetics Bacteriophages - isolation & purification Community composition Computational Biology CRISPR Dark matter Datasets DNA - genetics DNA sequencing DNA viruses DNA Viruses - classification DNA Viruses - genetics DNA Viruses - isolation & purification DNA, Viral - genetics Drug resistance Genetic diversity Genetic Variation Genomes Humans Metagenomics Microbiomes Microbiota Nucleotide sequence Phages Predation Purification Sequence Analysis, DNA Skin - virology Skin diseases Spatio-Temporal Analysis Structure-function relationships Taxonomy Virulence Virulence factors Virus-like particles Viruses
ISSN:	2161-2129, 2150-7511
Online Access:	Get full text
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