Efficacy and safety of apixaban vs warfarin in patients with atrial fibrillation and prior bioprosthetic valve replacement or valve repair: Insights from the ARISTOTLE trial

Background The optimal anticoagulation strategy for patients with atrial fibrillation (AF) and bioprosthetic valve (BPV) replacement or native valve repair remains uncertain. Hypothesis We evaluated the safety and efficacy of apixaban vs warfarin in patients with AF and a history of BPV replacement...

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Bibliographic Details
Published in:	Clinical cardiology (Mahwah, N.J.) Vol. 42; no. 5; pp. 568 - 571
Main Authors:	Guimarães, Patricia O., Pokorney, Sean D., Lopes, Renato D., Wojdyla, Daniel M., Gersh, Bernard J., Giczewska, Anna, Carnicelli, Anthony, Lewis, Basil S., Hanna, Michael, Wallentin, Lars, Vinereanu, Dragos, Alexander, John H., Granger, Christopher B.
Format:	Journal Article
Language:	English
Published:	New York Wiley Periodicals, Inc 01.05.2019 John Wiley & Sons, Inc
Subjects:	Aged Anticoagulants Anticoagulants - adverse effects Anticoagulants - therapeutic use apixaban atrial fibrillation Atrial Fibrillation - complications Atrial Fibrillation - diagnosis Atrial Fibrillation - drug therapy Bioprosthesis bioprosthetic valves Cardiac arrhythmia Catheters Clinical Investigations Factor Xa Inhibitors - adverse effects Factor Xa Inhibitors - therapeutic use Female Heart Valve Prosthesis Heart Valve Prosthesis Implantation - adverse effects Heart Valve Prosthesis Implantation - instrumentation Heart Valves - surgery Hemorrhage - chemically induced Humans Male Middle Aged Pyrazoles - adverse effects Pyrazoles - therapeutic use Pyridones - adverse effects Pyridones - therapeutic use Risk Factors Stroke - diagnosis Stroke - etiology Stroke - prevention & control Time Factors Treatment Outcome valve repair Warfarin - adverse effects Warfarin - therapeutic use bioprosthetic valves atrial fibrillation apixaban valve repair
ISSN:	0160-9289, 1932-8737, 1932-8737
Online Access:	Get full text
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