Activation and desensitization of the olfactory cAMP-gated transduction channel: identification of functional modules

Olfactory receptor neurons respond to odor stimulation with a receptor potential that results from the successive activation of cyclic AMP (cAMP)-gated, Ca(2+)-permeable channels and Ca(2+)-activated chloride channels. The cAMP-gated channels open at micromolar concentrations of their ligand and are...

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Veröffentlicht in:	The Journal of general physiology Jg. 134; H. 5; S. 397
Hauptverfasser:	Waldeck, Clemens, Vocke, Kerstin, Ungerer, Nicole, Frings, Stephan, Möhrlen, Frank
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.11.2009
Schlagworte:	Calcium - metabolism Calcium Signaling Cyclic AMP - metabolism Cyclic Nucleotide-Gated Cation Channels - genetics Cyclic Nucleotide-Gated Cation Channels - metabolism Electrophysiology Ion Channel Gating Mutagenesis, Site-Directed Olfactory Receptor Neurons - metabolism Protein Subunits - genetics Protein Subunits - metabolism
ISSN:	1540-7748, 1540-7748
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