Fueling Inflamm-Aging through Mitochondrial Dysfunction: Mechanisms and Molecular Targets

Among the complex determinants of aging, mitochondrial dysfunction has been in the spotlight for a long time. As the hub for many cellular functions, the maintenance of an adequate pool of functional mitochondria is crucial for tissue homeostasis. Their unique role in energy supply makes these organ...

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Veröffentlicht in:	International journal of molecular sciences Jg. 18; H. 5; S. 933
Hauptverfasser:	Picca, Anna, Lezza, Angela, Leeuwenburgh, Christiaan, Pesce, Vito, Calvani, Riccardo, Landi, Francesco, Bernabei, Roberto, Marzetti, Emanuele
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 28.04.2017 MDPI
Schlagworte:	Aging Alarmins - metabolism DNA, Mitochondrial - metabolism Humans Inflammation Mitochondria - genetics Mitochondria - metabolism Mitochondrial Degradation Mitochondrial DNA Mitochondrial Dynamics Molecular biology Oxidative Stress Review sterile inflammation mitophagy inflammasome mitochondrial quality control (MQC) TFAM damage-associated molecular patterns (DAMPs) mitochondrial biogenesis mitochondrial dynamics
ISSN:	1422-0067, 1661-6596, 1422-0067
Online-Zugang:	Volltext
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