Autophagy in Neurotrauma: Good, Bad, or Dysregulated

Autophagy is a physiological process that helps maintain a balance between the manufacture of cellular components and breakdown of damaged organelles and other toxic cellular constituents. Changes in autophagic markers are readily detectable in the spinal cord and brain following neurotrauma, includ...

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Bibliographic Details
Published in:	Cells (Basel, Switzerland) Vol. 8; no. 7; p. 693
Main Authors:	Wu, Junfang, Lipinski, Marta M.
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 10.07.2019 MDPI
Subjects:	Animals Apoptosis autophagic flux Autophagy Autophagy - physiology Biosynthesis Brain - metabolism Brain Injuries, Traumatic - metabolism Brain Injuries, Traumatic - physiopathology Cell cycle Chemokines Cytokines Disease Models, Animal Humans Kinases lysosomal damage Lysosomes - metabolism neuronal cell death Neurons - metabolism Neuroprotection Organelles Phagocytosis Physiology Proteins Review Spinal Cord - metabolism Spinal cord injuries Spinal Cord Injuries - metabolism Spinal Cord Injuries - physiopathology spinal cord injury Trauma Trauma, Nervous System - metabolism Trauma, Nervous System - physiopathology Traumatic brain injury United States > US autophagic flux spinal cord injury traumatic brain injury neuronal cell death autophagy lysosomal damage
ISSN:	2073-4409, 2073-4409
Online Access:	Get full text
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