Enhanced Expression of Human Endogenous Retroviruses, TRIM28 and SETDB1 in Autism Spectrum Disorder

Human endogenous retroviruses (HERVs) are relics of ancestral infections and represent 8% of the human genome. They are no longer infectious, but their activation has been associated with several disorders, including neuropsychiatric conditions. Enhanced expression of HERV-K and HERV-H envelope gene...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 23; no. 11; p. 5964
Main Authors:	Tovo, Pier-Angelo, Davico, Chiara, Marcotulli, Daniele, Vitiello, Benedetto, Daprà, Valentina, Calvi, Cristina, Montanari, Paola, Carpino, Andrea, Galliano, Ilaria, Bergallo, Massimiliano
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 25.05.2022 MDPI
Subjects:	Age Autism Spectrum Disorder - genetics Autistic children Brain Child Cytokines DNA methylation Endogenous Retroviruses - genetics Endogenous Retroviruses - metabolism Epigenetics Families & family life Gene Products, env - metabolism Genes Genome, Human Genomes Histone-Lysine N-Methyltransferase - genetics Histone-Lysine N-Methyltransferase - metabolism Humans Immune system Male Multiple Sclerosis - pathology Proteins Transcription Factors - genetics Tripartite Motif-Containing Protein 28 - genetics Tripartite Motif-Containing Protein 28 - metabolism SETDB1 TRIM28 autism spectrum disorder human endogenous retroviruses children
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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