Defining the Comprehensive Genomic Landscapes of Pancreatic Ductal Adenocarcinoma Using Real-World Endoscopic Aspiration Samples

Most patients with pancreatic ductal adenocarcinoma (PDAC) present with surgically unresectable cancer. As a result, endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is the most common biospecimen source available for diagnosis in treatment-naïve patients. Unfortunately, these limited s...

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Veröffentlicht in:	Clinical cancer research Jg. 27; H. 4; S. 1082
Hauptverfasser:	Semaan, Alexander, Bernard, Vincent, Lee, Jaewon J, Wong, Justin W, Huang, Jonathan, Swartzlander, Daniel B, Stephens, Bret M, Monberg, Maria E, Weston, Brian R, Bhutani, Manoop S, Chang, Kyle, Scheet, Paul A, Maitra, Anirban, Jakubek, Yasminka A, Guerrero, Paola A
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 15.02.2021
Schlagworte:	Aged Aged, 80 and over Carcinoma, Pancreatic Ductal - genetics Carcinoma, Pancreatic Ductal - mortality Carcinoma, Pancreatic Ductal - pathology Carcinoma, Pancreatic Ductal - therapy DNA Copy Number Variations DNA Mutational Analysis - methods Endoscopic Ultrasound-Guided Fine Needle Aspiration Feasibility Studies Female Genetic Heterogeneity Genomics Humans Male Middle Aged Mutation Pancreas - diagnostic imaging Pancreas - pathology Pancreatic Neoplasms - genetics Pancreatic Neoplasms - mortality Pancreatic Neoplasms - pathology Pancreatic Neoplasms - therapy Pilot Projects Prognosis Progression-Free Survival Whole Exome Sequencing
ISSN:	1557-3265, 1557-3265
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