Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

Tumor hypoxia is a negative prognostic factor that is implicated in oncogenic signal activation, immune escape, and resistance to treatment. Identifying the mechanistic role of hypoxia in immune escape and resistance to immune-checkpoint inhibitors may aid the identification of therapeutic targets....

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Vydané v:	Cancer immunology research Ročník 7; číslo 7; s. 1079
Hlavní autori:	Deng, Jie, Li, Jiannan, Sarde, Aurelien, Lines, J Louise, Lee, Yu-Chi, Qian, David C, Pechenick, Dov A, Manivanh, Richard, Le Mercier, Isabelle, Lowrey, Christopher H, Varn, Frederick S, Cheng, Chao, Leib, David A, Noelle, Randolph J, Mabaera, Rodwell
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.07.2019
ISSN:	2326-6074, 2326-6074
On-line prístup:	Zistit podrobnosti o prístupe
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