Single-Cell Transcriptomics of Pancreatic Cancer Precursors Demonstrates Epithelial and Microenvironmental Heterogeneity as an Early Event in Neoplastic Progression

Early detection of pancreatic ductal adenocarcinoma (PDAC) remains elusive. Precursor lesions of PDAC, specifically intraductal papillary mucinous neoplasms (IPMNs), represent a pathway to invasive neoplasia, although the molecular correlates of progression remain to be fully elucidated. Single-cell...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Clinical cancer research Jg. 25; H. 7; S. 2194
Hauptverfasser:	Bernard, Vincent, Semaan, Alexander, Huang, Jonathan, San Lucas, F Anthony, Mulu, Feven C, Stephens, Bret M, Guerrero, Paola A, Huang, Yanqing, Zhao, Jun, Kamyabi, Nabiollah, Sen, Subrata, Scheet, Paul A, Taniguchi, Cullen M, Kim, Michael P, Tzeng, Ching-Wei, Katz, Matthew H, Singhi, Aatur D, Maitra, Anirban, Alvarez, Hector A
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.04.2019
Schlagworte:	Adenocarcinoma, Mucinous - genetics Carcinoma, Pancreatic Ductal - genetics Disease Progression Humans Pancreatic Neoplasms - genetics Phenotype Tumor Microenvironment
ISSN:	1557-3265, 1557-3265
Online-Zugang:	Weitere Angaben
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!