Phosphatidylserine enhances anti-inflammatory effects of reconstituted HDL in macrophages via distinct intracellular pathways

Phosphatidylserine (PS) is a minor phospholipid constituent of high-density lipoprotein (HDL) that exhibits potent anti-inflammatory activity. It remains indeterminate whether PS incorporation can enhance anti-inflammatory effects of reconstituted HDL (rHDL). Human macrophages were treated with rHDL...

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Bibliographic Details

Published in:	The FASEB journal Vol. 36; no. 5; p. e22274
Main Authors:	Darabi, Maryam, Lhomme, Marie, Dahik, Veronica D, Guillas, Isabelle, Frisdal, Eric, Tubeuf, Emilie, Poupel, Lucie, Patel, Mili, Gautier, Emmanuel L, Huby, Thierry, Guerin, Maryse, Rye, Kerry-Anne, Lesnik, Philippe, Le Goff, Wilfried, Kontush, Anatol
Format:	Journal Article
Language:	English
Published:	United States 01.05.2022
Subjects:	Animals Anti-Inflammatory Agents - metabolism Anti-Inflammatory Agents - pharmacology Lipoproteins, HDL - metabolism Macrophages - metabolism Mice p38 Mitogen-Activated Protein Kinases - metabolism Phosphatidylserines - metabolism atherosclerosis rHDL phospholipids inflammation
ISSN:	1530-6860, 1530-6860
Online Access:	Get more information
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