IQuant: An automated pipeline for quantitative proteomics based upon isobaric tags

Quantitative proteomics technology based on isobaric tags is playing an important role in proteomic investigation. In this paper, we present an automated software, named IQuant, which integrates a postprocessing tool of protein identification and advanced statistical algorithms to process the MS/MS...

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Bibliographic Details
Published in:Proteomics (Weinheim) Vol. 14; no. 20; pp. 2280 - 2285
Main Authors: Wen, Bo, Zhou, Ruo, Feng, Qiang, Wang, Quanhui, Wang, Jun, Liu, Siqi
Format: Journal Article
Language:English
Published: Germany Blackwell Publishing Ltd 01.10.2014
Subjects:
Bioinformatics
Internet
Isobaric tags
Mass spectrometry
Peptides - analysis
Protein quantification
Proteins - analysis
Proteomics - methods
Software
Tandem Mass Spectrometry - methods
Technology
Technology
Bioinformatics
Isobaric tags
Mass spectrometry
Protein quantification
ISSN:1615-9853, 1615-9861, 1615-9861
Online Access:Get full text
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Summary:Quantitative proteomics technology based on isobaric tags is playing an important role in proteomic investigation. In this paper, we present an automated software, named IQuant, which integrates a postprocessing tool of protein identification and advanced statistical algorithms to process the MS/MS signals generated from the peptides labeled by isobaric tags and aims at proteomics quantification. The software of IQuant, which is freely downloaded at http://sourceforge.net/projects/iquant/, can run from a graphical user interface and a command‐line interface, and can work on both Windows and Linux systems.
Bibliography:973 Program of China - No. 2010CB912703
ark:/67375/WNG-TMS8FWQ3-6
istex:6E92D1347EC1E86FEA8E7007A3A4FDD29E51CD5E
Nature Science Foundation of China - No. 91131009
ArticleID:PMIC7812
Colour Online: See the article online to view Fig. 2 in colour.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1615-9853
1615-9861
1615-9861
DOI:10.1002/pmic.201300361