Evaluating the Influence of Quality Control Decisions and Software Algorithms on SNP Calling for the Affymetrix 6.0 SNP Array Platform

Objective: Our goal was to evaluate the influence of quality control (QC) decisions using two genotype calling algorithms, CRLMM and Birdseed, designed for the Affymetrix SNP Array 6.0. Methods: Various QC options were tried using the two algorithms and comparisons were made on subject and call rate...

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Bibliographic Details
Published in:	Human heredity Vol. 71; no. 4; pp. 221 - 233
Main Authors:	de Andrade, Mariza, Atkinson, Elizabeth J., Bamlet, William R., Matsumoto, Martha E., Maharjan, Sooraj, Slager, Susan L., Vachon, Celine M., Cunningham, Julie M., Kardia, Sharon L.R.
Format:	Journal Article
Language:	English
Published:	Basel, Switzerland S. Karger AG 01.01.2011
Subjects:	Adult Algorithms Genotype Genotype & phenotype Humans Oligonucleotide Array Sequence Analysis - methods Original Paper Polymorphism Polymorphism, Single Nucleotide Quality Control Software Birdseed Genotype call Association CRLMM Quality control decisions
ISSN:	0001-5652, 1423-0062, 1423-0062
Online Access:	Get full text
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