Enzyme‐Responsive Polymer Nanoparticles via Ring‐Opening Metathesis Polymerization‐Induced Self‐Assembly

Open‐to‐air aqueous‐phase ring‐opening metathesis polymerization‐induced self‐assembly (ROMPISA) is reported for forming well‐defined peptide polymer nanoparticles at room temperature and with high solids concentrations (10 w/w%). For these materials, ROMPISA is shown to provide control over molecul...

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Veröffentlicht in:	Macromolecular rapid communications. Jg. 40; H. 2; S. e1800467 - n/a
Hauptverfasser:	Wright, Daniel B., Thompson, Matthew P., Touve, Mollie A., Carlini, Andrea S., Gianneschi, Nathan C.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Germany Wiley Subscription Services, Inc 01.01.2019
Schlagworte:	Amino Acid Sequence Assembly block copolymers Chemistry Techniques, Synthetic - methods Enzymes Hydrophobic and Hydrophilic Interactions Metathesis Microscopy, Electron, Transmission Molecular Weight Nanoparticles Nanoparticles - chemistry Nanoparticles - ultrastructure Peptides Peptides - chemical synthesis Peptides - chemistry Peptides - metabolism Polymerization Polymers Polymers - chemical synthesis Polymers - chemistry Polymers - metabolism Protein Structure, Secondary Proteolysis ROMPISA self‐assembly Thermolysin Thermolysin - metabolism block copolymers self-assembly peptides ROMPISA
ISSN:	1022-1336, 1521-3927, 1521-3927
Online-Zugang:	Volltext
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