Genome-wide significant risk factors for Alzheimer’s disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment

Few data are available concerning the role of risk markers for Alzheimer’s disease (AD) in progression to AD dementia among subjects with mild cognitive impairment (MCI). We therefore investigated the role of well-known AD-associated single-nucleotide polymorphism (SNP) in the progression from MCI t...

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Veröffentlicht in:	Molecular psychiatry Jg. 22; H. 1; S. 153 - 160
Hauptverfasser:	Lacour, A, Espinosa, A, Louwersheimer, E, Heilmann, S, Hernández, I, Wolfsgruber, S, Fernández, V, Wagner, H, Rosende-Roca, M, Mauleón, A, Moreno-Grau, S, Vargas, L, Pijnenburg, Y A L, Koene, T, Rodríguez-Gómez, O, Ortega, G, Ruiz, S, Holstege, H, Sotolongo-Grau, O, Kornhuber, J, Peters, O, Frölich, L, Hüll, M, Rüther, E, Wiltfang, J, Scherer, M, Riedel-Heller, S, Alegret, M, Nöthen, M M, Scheltens, P, Wagner, M, Tárraga, L, Jessen, F, Boada, M, Maier, W, van der Flier, W M, Becker, T, Ramirez, A, Ruiz, A
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 01.01.2017 Nature Publishing Group
Schlagworte:	38/43 45/22 45/77 631/208 692/53 Aged Aged, 80 and over Alzheimer Disease - genetics Apolipoprotein E4 - genetics Behavioral Sciences Biological Psychology Biomarkers Clusterin - genetics Cognitive Dysfunction - genetics Dementia Dementia - genetics Disease Progression Female Follow-Up Studies Genetic Predisposition to Disease Genome-Wide Association Study - methods Humans Male Medicine Medicine & Public Health Middle Aged Neurosciences Original original-article Pharmacotherapy Polymorphism, Single Nucleotide - genetics Psychiatry Risk Factors
ISSN:	1359-4184, 1476-5578
Online-Zugang:	Volltext
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