A Plasma-Derived Protein-Metabolite Multiplexed Panel for Early-Stage Pancreatic Cancer

We applied a training and testing approach to develop and validate a plasma metabolite panel for the detection of early-stage pancreatic ductal adenocarcinoma (PDAC) alone and in combination with a previously validated protein panel for early-stage PDAC. A comprehensive metabolomics platform was ini...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute Jg. 111; H. 4; S. 372
Hauptverfasser:	Fahrmann, Johannes F, Bantis, Leonidas E, Capello, Michela, Scelo, Ghislaine, Dennison, Jennifer B, Patel, Nikul, Murage, Eunice, Vykoukal, Jody, Kundnani, Deepali L, Foretova, Lenka, Fabianova, Eleonora, Holcatova, Ivana, Janout, Vladimir, Feng, Ziding, Yip-Schneider, Michele, Zhang, Jianjun, Brand, Randall, Taguchi, Ayumu, Maitra, Anirban, Brennan, Paul, Max Schmidt, C, Hanash, Samir
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.04.2019
Schlagworte:	Adenocarcinoma, Mucinous - genetics Adenocarcinoma, Mucinous - metabolism Adenocarcinoma, Mucinous - pathology Biomarkers, Tumor - blood Biomarkers, Tumor - genetics Carcinoma, Pancreatic Ductal - genetics Carcinoma, Pancreatic Ductal - metabolism Carcinoma, Pancreatic Ductal - pathology Carcinoma, Papillary - genetics Carcinoma, Papillary - metabolism Carcinoma, Papillary - pathology Case-Control Studies Follow-Up Studies Humans Metabolome Neoplasm Invasiveness Neoplasm Staging Pancreatic Neoplasms - genetics Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology Transcriptome
ISSN:	1460-2105, 1460-2105
Online-Zugang:	Weitere Angaben
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