Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology

Organotypic co-cultures bridge the gap between standard two-dimensional culture and mouse models. Such assays increase the fidelity of pre-clinical studies, to better inform lead compound development and address the increasing attrition rates of lead compounds within the pharmaceutical industry, whi...

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Veröffentlicht in:Scientific reports Jg. 7; H. 1; S. 16887 - 15
Hauptverfasser: Conway, James R. W., Vennin, Claire, Cazet, Aurélie S., Herrmann, David, Murphy, Kendelle J., Warren, Sean C., Wullkopf, Lena, Boulghourjian, Alice, Zaratzian, Anaiis, Da Silva, Andrew M., Pajic, Marina, Morton, Jennifer P., Cox, Thomas R., Timpson, Paul
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London Nature Publishing Group UK 04.12.2017
Nature Publishing Group
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ISSN:2045-2322, 2045-2322
Online-Zugang:Volltext
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