Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity

Red blood cell storage in the blood bank promotes the progressive accumulation of metabolic alterations that may ultimately impact the erythrocyte capacity to cope with oxidant stressors. However, the metabolic underpinnings of the capacity of RBCs to resist oxidant stress and the potential impact o...

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Veröffentlicht in:	Haematologica (Roma) Jg. 106; H. 5; S. 1290 - 1302
Hauptverfasser:	D'Alessandro, Angelo, Fu, Xiaoyun, Kanias, Tamir, Reisz, Julie A, Culp-Hill, Rachel, Guo, Yuelong, Gladwin, Mark T, Page, Grier, Kleinman, Steven, Lanteri, Marion, Stone, Mars, Busch, Michael P, Zimring, James C
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Italy Fondazione Ferrata Storti 01.05.2021 Ferrata Storti Foundation
Schlagworte:	Adult Antioxidants Blood Preservation Erythrocytes Ethnicity Female Glucose Glucosephosphate Dehydrogenase - genetics Hemolysis Humans Male Middle Aged Phosphates
ISSN:	0390-6078, 1592-8721, 1592-8721
Online-Zugang:	Volltext
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