The regulation and function of CD20: an “enigma” of B-cell biology and targeted therapy

The introduction of anti-CD20 monoclonal antibodies such as rituximab, ofatumumab, or obinutuzumab improved the therapy of B-cell malignancies even though the precise physiological role and regulation of CD20 remains unclear. Furthermore, CD20 expression is highly variable between different B-cell m...

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Vydané v:	Haematologica (Roma) Ročník 105; číslo 6; s. 1494 - 1506
Hlavní autori:	Pavlasova, Gabriela, Mraz, Marek
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Italy Ferrata Storti Foundation 01.06.2020
Predmet:	Antibodies, Monoclonal Antigens, CD20 B-Lymphocytes Humans Leukemia, Lymphocytic, Chronic, B-Cell Pyrimidines Review Rituximab
ISSN:	0390-6078, 1592-8721, 1592-8721
On-line prístup:	Získať plný text
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