The regulation and function of CD20: an “enigma” of B-cell biology and targeted therapy

The introduction of anti-CD20 monoclonal antibodies such as rituximab, ofatumumab, or obinutuzumab improved the therapy of B-cell malignancies even though the precise physiological role and regulation of CD20 remains unclear. Furthermore, CD20 expression is highly variable between different B-cell m...

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Bibliographic Details

Published in:	Haematologica (Roma) Vol. 105; no. 6; pp. 1494 - 1506
Main Authors:	Pavlasova, Gabriela, Mraz, Marek
Format:	Journal Article
Language:	English
Published:	Italy Ferrata Storti Foundation 01.06.2020
Subjects:	Antibodies, Monoclonal Antigens, CD20 B-Lymphocytes Humans Leukemia, Lymphocytic, Chronic, B-Cell Pyrimidines Review Rituximab
ISSN:	0390-6078, 1592-8721, 1592-8721
Online Access:	Get full text
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