Pathogenic Old World arenaviruses inhibit TLR2/Mal-dependent proinflammatory cytokines in vitro

Lymphocytic choriomeningitis virus (LCMV), the prototype arenavirus, and Lassa virus (LASV), the causative agent of Lassa fever (LF), have extensive strain diversity and significant variations in pathogenicity for humans and experimental animals. The WE strain of LCMV (LCMV-WE), but not the Armstron...

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Vydáno v:	Journal of virology Ročník 86; číslo 13; s. 7216
Hlavní autoři:	Hayes, Melissa W, Carrion, Jr, Ricardo, Nunneley, Jerritt, Medvedev, Andrei E, Salvato, Maria S, Lukashevich, Igor S
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.07.2012
Témata:	Animals Cell Line Cytokines - antagonists & inhibitors Humans Immune Evasion Lassa virus - immunology Lassa virus - pathogenicity Lymphocytic choriomeningitis virus - immunology Lymphocytic choriomeningitis virus - pathogenicity Membrane Transport Proteins - immunology Mice Mice, Inbred C57BL Mice, Knockout Myelin and Lymphocyte-Associated Proteolipid Proteins Myelin Proteins - antagonists & inhibitors Myelin Proteins - immunology NF-kappa B - antagonists & inhibitors NF-kappa B - immunology Proteolipids - antagonists & inhibitors Proteolipids - immunology Toll-Like Receptor 2 - antagonists & inhibitors Toll-Like Receptor 2 - immunology
ISSN:	1098-5514, 1098-5514
On-line přístup:	Zjistit podrobnosti o přístupu
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