Fibrin(ogen) in human disease: both friend and foe

Fibrinogen is an abundant protein synthesized in the liver, present in human blood plasma at concentrations ranging from 1.5-4 g/L in healthy individuals with a normal half-life of 3-5 days. With fibrin, produced by thrombin-mediated cleavage, fibrinogen plays important roles in many physiological p...

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Bibliographic Details

Published in:	Haematologica (Roma) Vol. 105; no. 2; pp. 284 - 296
Main Authors:	Vilar, Rui, Fish, Richard J., Casini, Alessandro, Neerman-Arbez, Marguerite
Format:	Journal Article
Language:	English
Published:	Italy Ferrata Storti Foundation 01.02.2020
Subjects:	Fibrin Fibrinogen Humans Review Thrombin
ISSN:	0390-6078, 1592-8721, 1592-8721
Online Access:	Get full text
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