Identification of candidate aberrantly methylated and differentially expressed genes in Esophageal squamous cell carcinoma

Aberrant methylated genes (DMGs) play an important role in the etiology and pathogenesis of esophageal squamous cell carcinoma (ESCC). In this study, we aimed to integrate three cohorts profile datasets to ascertain aberrant methylated-differentially expressed genes and pathways associated with ESCC...

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Bibliographic Details
Published in:	Scientific reports Vol. 10; no. 1; p. 9735
Main Authors:	Han, Bao-Ai, Yang, Xiu-Ping, Hosseini, Davood K, Zhang, Po, Zhang, Ya, Yu, Jin-Tao, Chen, Shan, Zhang, Fan, Zhou, Tao, Sun, Hai-Ying
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 16.06.2020 Nature Publishing Group
Subjects:	119/118 631/67/2324 631/67/68/2486 9/10 AKT protein Bioinformatics Biomarkers, Tumor - genetics Cell cycle Cohort Studies Computational Biology Databases, Genetic DNA methylation DNA Methylation - genetics DNA microarrays Esophageal cancer Esophageal Neoplasms - genetics Esophageal Squamous Cell Carcinoma - genetics Esophageal Squamous Cell Carcinoma - metabolism Esophagus Etiology Gene expression Gene Expression - genetics Gene Expression Profiling Gene Expression Regulation, Neoplastic - genetics Gene Ontology Gene Regulatory Networks Genomes Humanities and Social Sciences Humans Methylation Microarray Analysis Molecular modelling multidisciplinary Protein interaction Protein Interaction Maps - genetics Science Science (multidisciplinary) Signal transduction Signal Transduction - genetics Software Squamous cell carcinoma Transcriptome - genetics
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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