Solution NMR backbone assignments of the N-terminal Zα-linker-Zβ segment from Homo sapiens ADAR1p150

Adenosine-to-inosine (A-to-I) editing of a subset of RNAs in a eukaryotic cell is required in order to avoid triggering the innate immune system. Editing is carried out by ADAR1, which exists as short (p110) and long (p150) isoforms. ADAR1p150 is mostly cytoplasmic, possesses a Z-RNA binding domain...

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Veröffentlicht in:	Biomolecular NMR assignments Jg. 15; H. 2; S. 273 - 279
Hauptverfasser:	Nichols, Parker J., Henen, Morkos A., Vicens, Quentin, Vögeli, Beat
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Dordrecht Springer Netherlands 01.10.2021 Springer Nature B.V
Schlagworte:	Adenosine Adenosine Deaminase - chemistry Adenosine Deaminase - metabolism Amino Acid Sequence Biochemistry Biological and Medical Physics Biophysics Humans Immune response Innate immunity Isoforms N-Terminus NMR Nuclear magnetic resonance Nuclear Magnetic Resonance, Biomolecular Physics Physics and Astronomy Polymer Sciences Protein Domains Protein structure RNA-Binding Proteins - chemistry RNA-Binding Proteins - metabolism Secondary structure Solutions Editing Protein domains Z-RNA Protein structure and dynamics Backbone chemical shift assignment ADAR1
ISSN:	1874-2718, 1874-270X, 1874-270X
Online-Zugang:	Volltext
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