CT radiomics associations with genotype and stromal content in pancreatic ductal adenocarcinoma

Purpose The aim of this study was to investigate the relationship between CT imaging phenotypes and genetic and biological characteristics in pancreatic ductal adenocarcinoma (PDAC). Methods In this retrospective study, consecutive patients between April 2015 and June 2016 who underwent PDAC resecti...

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Bibliographic Details
Published in:	Abdominal imaging Vol. 44; no. 9; pp. 3148 - 3157
Main Authors:	Attiyeh, Marc A., Chakraborty, Jayasree, McIntyre, Caitlin A., Kappagantula, Rajya, Chou, Yuting, Askan, Gokce, Seier, Kenneth, Gonen, Mithat, Basturk, Olca, Balachandran, Vinod P., Kingham, T. Peter, D’Angelica, Michael I., Drebin, Jeffrey A., Jarnagin, William R., Allen, Peter J., Iacobuzio-Donahue, Christine A., Simpson, Amber L., Do, Richard K.
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.09.2019 Springer Nature B.V
Subjects:	Adenocarcinoma Adenocarcinoma - diagnostic imaging Adenocarcinoma - genetics Aged Carcinoma, Pancreatic Ductal - diagnostic imaging Carcinoma, Pancreatic Ductal - genetics Cohort Studies Computed tomography Deoxyribonucleic acid DNA DNA sequencing Feature extraction Female Gastroenterology Genes Genotype Genotypes Hepatology Humans Imaging Immunohistochemistry Male Medical imaging Medicine Medicine & Public Health Middle Aged Mutation p53 Protein Pancreas Pancreas - diagnostic imaging Pancreatic cancer Pancreatic Neoplasms Pancreatic Neoplasms - diagnostic imaging Pancreatic Neoplasms - genetics Phenotypes Precision medicine Prediction models Radiology Radiomics Regression analysis Regression models Retrospective Studies Smad4 protein Tomography, X-Ray Computed - methods Tumors Pancreatic neoplasm Survival Radiogenomics Genomics Computational biology
ISSN:	2366-004X, 2366-0058, 2366-0058
Online Access:	Get full text
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