Statistical Analysis in the German National Cohort (NAKO) – Specific Aspects and General Recommendations

The German National Cohort (NAKO) is an ongoing, prospective multicenter cohort study, which started recruitment in 2014 and includes more than 205,000 women and men aged 19–74 years. The study data will be available to the global research community for analyses. Although the ultimate decision about...

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Vydáno v:European journal of epidemiology Ročník 37; číslo 4; s. 429 - 436
Hlavní autoři: Kuss, Oliver, Becher, Heiko, Wienke, Andreas, Ittermann, Till, Ostrzinski, Stefan, Schipf, Sabine, Schmidt, Carsten O, Leitzmann, Michael, Pischon, Tobias, Krist, Lilian, Roll, Stephanie, Sand, Matthias, Pohlabeln, Hermann, Rach, Stefan, Jöckel, Karl-Heinz, Stang, Andreas, Mueller, Ulrich A, Werdecker, Andrea, Westerman, Ronny, Greiser, Karin H, Michels, Karin B
Médium: Journal Article
Jazyk:angličtina
Vydáno: Dordrecht Springer Netherlands 01.04.2022
Springer Nature B.V
Témata:
Biometrics
Calibration
Cancer
Cardiology
Cardiovascular disease
Cohort analysis
Cohort Studies
Cohort Update
Data collection
Data dictionaries
Decision analysis
Diabetes
Epidemiology
Female
Health care
Humans
Infectious Diseases
Informatics
Longitudinal Studies
Male
Medicine
Medicine & Public Health
Mortality
Oncology
Preventive medicine
Prospective Studies
Public Health
Questionnaires
Research Design
Sampling designs
Statistical analysis
Statistics
Biostatistics
Prospective studies
Follow-Up studies
Data interpretation, statistical
Cohort Studies
ISSN:0393-2990, 1573-7284, 1573-7284
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Shrnutí:The German National Cohort (NAKO) is an ongoing, prospective multicenter cohort study, which started recruitment in 2014 and includes more than 205,000 women and men aged 19–74 years. The study data will be available to the global research community for analyses. Although the ultimate decision about the analytic methods will be made by the respective investigator, in this paper we provide the basis for a harmonized approach to the statistical analyses in the NAKO. We discuss specific aspects of the study (e.g., data collection, weighting to account for the sampling design), but also give general recommendations which may apply to other large cohort studies as well.
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ISSN:0393-2990
1573-7284
1573-7284
DOI:10.1007/s10654-022-00880-7