Structural basis for disassembly of katanin heterododecamers

The reorganization of microtubules in mitosis, meiosis, and development requires the microtubule-severing activity of katanin. Katanin is a heterodimer composed of an TPase ssociated with diverse cellular ctivities (AAA) subunit and a regulatory subunit. Microtubule severing requires ATP hydrolysis...

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Bibliographic Details
Published in:	The Journal of biological chemistry Vol. 293; no. 27; p. 10590
Main Authors:	Nithianantham, Stanley, McNally, Francis J, Al-Bassam, Jawdat
Format:	Journal Article
Language:	English
Published:	United States 06.07.2018
Subjects:	Adenosine Triphosphatases - chemistry Adenosine Triphosphatases - metabolism Animals Caenorhabditis elegans - enzymology Caenorhabditis elegans Proteins - chemistry Caenorhabditis elegans Proteins - metabolism Crystallography, X-Ray Humans Katanin - chemistry Katanin - metabolism Meiosis Microtubules Protein Conformation Protein Multimerization Spindle Apparatus X-ray crystallography microtubule microtubule-associated protein (MAP) tubulin meiosis mitosis
ISSN:	1083-351X, 1083-351X
Online Access:	Get more information
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