Early remodeling and loss of light-induced dilation of retinal small arteries in CADASIL

A major hurdle to therapeutic development in cerebral small vessel diseases is the lack of in-vivo method that can be used repeatedly for evaluating directly cerebral microvessels. We hypothesised that Adaptive Optics (AO), which allows resolution images up to 1-2 μm/pixel at retinal level, could pr...

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Bibliographic Details
Published in:	Journal of cerebral blood flow and metabolism Vol. 44; no. 7; p. 1089
Main Authors:	Paques, Michel, Krivosic, Valérie, Castro-Farias, Daniela, Dulière, Cédric, Hervé, Dominique, Chaumette, Céline, Rossant, Florence, Taleb, Abbas, Lebenberg, Jessica, Jouvent, Eric, Tadayoni, Ramin, Chabriat, Hugues
Format:	Journal Article
Language:	English
Published:	United States 01.07.2024
Subjects:	Adult Aged CADASIL - diagnostic imaging CADASIL - pathology CADASIL - physiopathology Female Humans Light Male Middle Aged Retinal Artery - diagnostic imaging Retinal Artery - pathology Retinal Artery - physiopathology Vascular Remodeling - physiology Vasodilation - physiology adaptive optics CADASIL functional remodeling retinal vessels
ISSN:	1559-7016, 1559-7016
Online Access:	Get more information
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