Oracle and Adaptive Compound Decision Rules for False Discovery Rate Control

We develop a compound decision theory framework for multiple-testing problems and derive an oracle rule based on the z values that minimizes the false nondiscovery rate (FNR) subject to a constraint on the false discovery rate (FDR). We show that many commonly used multiple-testing procedures, which...

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Veröffentlicht in:	Journal of the American Statistical Association Jg. 102; H. 479; S. 901 - 912
Hauptverfasser:	Sun, Wenguang, Cai, T. Tony
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Alexandria, VA Taylor & Francis 01.09.2007 American Statistical Association Taylor & Francis Ltd
Schlagworte:	Adaptive procedure Applications Applied statistics Compound decision rule Decision analysis Decision making Decision theory Density estimation Discovery Exact sciences and technology False discovery rate False positive errors General topics HIV Human immunodeficiency virus Hypothesis testing Local false discovery rate Mathematical procedures Mathematics Monotone likelihood ratio Multivariate analysis Null hypothesis Oracles P values Probability and statistics Proportions Rules Sciences and techniques of general use Significance tests Statistical methods Statistical models Statistics Tests Theory and Methods Weighted classification Non parametric estimation Multivariate analysis Microarray Multiple decision Hypothesis test Statistical test Law of large numbers P value Oracle Compound decision rule Human Adaptive procedure Data analysis Retroviridae Statistical estimation Statistical decision Monotone likelihood ratio Lentivirus Decision rule Weighted classification Virus Statistical method Decision theory Local false discovery rate False discovery rate Human immunodeficiency virus Application
ISSN:	0162-1459, 1537-274X
Online-Zugang:	Volltext
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