Periosteal matrix-derived hydrogel promotes bone repair through an early immune regulation coupled with enhanced angio- and osteogenesis

Bone healing is a complex physiological process initiated by early regulation of the inflammatory immunity and entails multiple events including angiogenesis, osteogenic differentiation, and biomineralization. Here, we fabricated an injectable periosteal extracellular matrix (PEM) hydrogel that dyna...

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Bibliographic Details
Published in:	Biomaterials Vol. 227; p. 119552
Main Authors:	Qiu, Pengcheng, Li, Mobai, Chen, Kai, Fang, Bin, Chen, Pengfei, Tang, Zhibin, Lin, Xianfeng, Fan, Shunwu
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01.01.2020
Subjects:	Angiogenesis Animals bioactive properties biocompatible materials Biomineralization blood vessels body fluids bone formation Bone Regeneration bones Cell Differentiation collagen Decellularized periosteum matrix hydrogel Early inflammatory immune regulation extracellular matrix Hydrogels immunity in vitro studies Macrophages osteoblasts Osteogenesis Rats Tissue Engineering Biomineralization Decellularized periosteum matrix hydrogel Angiogenesis Early inflammatory immune regulation Macrophages Bone regeneration
ISSN:	0142-9612, 1878-5905, 1878-5905
Online Access:	Get full text
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