Correlates of Peripheral Blood Mitochondrial DNA Content in a General Population

Accumulation of mitochondrial DNA (mtDNA) mutations leads to alterations of mitochondrial biogenesis and function that might produce a decrease in mtDNA content within cells. This implies that mtDNA content might be a potential biomarker associated with oxidative stress and inflammation. However, da...

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Vydané v:	American journal of epidemiology Ročník 183; číslo 2; s. 138
Hlavní autori:	Knez, Judita, Winckelmans, Ellen, Plusquin, Michelle, Thijs, Lutgarde, Cauwenberghs, Nicholas, Gu, Yumei, Staessen, Jan A, Nawrot, Tim S, Kuznetsova, Tatiana
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 15.01.2016
Predmet:	Age Distribution Belgium Biomarkers - blood DNA, Mitochondrial - blood Female Healthy Volunteers Hormone Replacement Therapy - adverse effects Humans Inflammation - genetics Leukocyte Count Male Middle Aged Oxidative Stress - genetics Platelet Count Real-Time Polymerase Chain Reaction Sex Distribution Belgium general population mitochondrial DNA peripheral blood
ISSN:	1476-6256, 1476-6256
On-line prístup:	Zistit podrobnosti o prístupe
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