Novel Role of the SIRT1 in Endocrine and Metabolic Diseases

Silent information regulator 1 (SIRT1), a highly conserved NAD -dependent deacetylase, is a cellular regulator that has received extensive attention in recent years and regarded as a sensor of cellular energy and metabolism. The accumulated evidence suggests that SIRT1 is involved in the development...

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Veröffentlicht in:	International journal of biological sciences Jg. 19; H. 2; S. 484 - 501
Hauptverfasser:	Lu, Chenxi, Zhao, Huadong, Liu, Yanqing, Yang, Zhi, Yao, Hairong, Liu, Tong, Gou, Tiantian, Wang, Li, Zhang, Juan, Tian, Ye, Yang, Yang, Zhang, Huan
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Australia Ivyspring International Publisher Pty Ltd 2023 Ivyspring International Publisher
Schlagworte:	Adipocytes Aging Apoptosis Autophagy Biomarkers Biomarkers - metabolism Deacetylation Diabetes Diabetes mellitus Endocrine system Endocrine System Diseases - diagnosis Endocrine System Diseases - drug therapy Endocrine System Diseases - metabolism Energy metabolism Female reproductive system Gene expression Glucose Histones Humans Hyperlipidemia Hypertension Hyperuricemia Insulin Kinases Lipids Localization Lysine Mammals Melatonin Metabolic Diseases - diagnosis Metabolic Diseases - drug therapy Metabolic Diseases - metabolism Metabolic disorders Molecular Targeted Therapy Osteoporosis Oxidative stress Pancreas Physiology Polycystic ovary syndrome Proteins Review Senescence SIRT1 protein Sirtuin 1 - metabolism Therapeutic targets Transcription factors Transcription Factors - metabolism inhibitors agonists SIRT1 endocrine metabolic
ISSN:	1449-2288, 1449-2288
Online-Zugang:	Volltext
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