Mitochondrial DNA sequencing reveals association of variants and haplogroup M33a2′3 with High altitude pulmonary edema susceptibility in Indian male lowlanders

High Altitude Pulmonary Edema (HAPE) is a threatening disorder caused due to acute exposure to high altitude above 3000 m. Apart from multiple factors involved, the genetic factors also play an important function in the pathogenesis of HAPE. This study aims to evaluate the role of mtDNA polymorphism...

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Bibliographic Details
Published in:	Scientific reports Vol. 9; no. 1; pp. 1 - 10
Main Authors:	Sharma, Swati, Singh, Sayar, Gupta, Rajinder K., Ganju, Lilly, Singh, Shashi Bala, Kumar, Bhuvnesh, Singh, Yamini
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 29.07.2019 Nature Publishing Group
Subjects:	45 45/22 45/23 45/29 45/77 631/208/205 631/208/726/2129 Altitude Copy number DNA sequencing Edema Etiology Genetic factors High-altitude environments Humanities and Social Sciences Mitochondrial DNA multidisciplinary Science Science (multidisciplinary)
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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