Crossing the Blood–Brain Barrier: Recent Advances in Drug Delivery to the Brain

CNS disorders are on the rise despite advancements in our understanding of their pathophysiological mechanisms. A major hurdle to the treatment of these disorders is the blood–brain barrier (BBB), which serves as an arduous janitor to protect the brain. Many drugs are being discovered for CNS disord...

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Vydané v:	CNS drugs Ročník 31; číslo 2; s. 109 - 133
Hlavní autori:	Patel, Mayur M., Patel, Bhoomika M.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Cham Springer International Publishing 01.02.2017 Springer Nature B.V
Predmet:	Alzheimer's disease Animals Biodegradability Biological Transport Blood-brain barrier Blood-Brain Barrier - metabolism Brain - metabolism Central nervous system Central Nervous System Diseases - drug therapy Clinical trials Convection Drug Carriers - chemistry Drug delivery Drug Delivery Systems Drug Design Drug development Endocytosis Exosomes Humans Liposomes Medicine Medicine & Public Health Micelles Microspheres Nanoparticles Nervous system Neurology Neurosciences Parkinson's disease Permeability Pharmaceuticals Pharmacotherapy Physiology Prescription drugs Protein transport Psychiatry Psychopharmacology Quantum dots Review Article Tissue Distribution Ultrasonic imaging Brain Endothelial Cell PLGA Microsphere Brain Capillary Endothelial Cell Nanostructured Lipid Carrier Fingolimod
ISSN:	1172-7047, 1179-1934, 1179-1934
On-line prístup:	Získať plný text
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