Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models

The recent emergence of novel pathogenic human and animal coronaviruses has highlighted the need for antiviral therapies that are effective against a spectrum of these viruses. We have used several strains of murine hepatitis virus (MHV) in cell culture and in vivo in mouse models to investigate the...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of virology Jg. 81; H. 11; S. 5637
Hauptverfasser:	Burrer, Renaud, Neuman, Benjamin W, Ting, Joey P C, Stein, David A, Moulton, Hong M, Iversen, Patrick L, Kuhn, Peter, Buchmeier, Michael J
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.06.2007
Schlagworte:	Animals Antiviral Agents - pharmacology Cercopithecus aethiops Coronavirus Infections - drug therapy Coronavirus Infections - virology Disease Models, Animal Male Mice Mice, Inbred C57BL Morpholines - pharmacology Murine hepatitis virus - drug effects Murine hepatitis virus - genetics Oligonucleotides, Antisense - pharmacology Vero Cells Viral Load
ISSN:	0022-538X
Online-Zugang:	Weitere Angaben
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!