IL-6/NOS2 inflammatory signals regulate MMP-9 and MMP-2 activity and disease outcome in nasopharyngeal carcinoma patients

The role of nitric oxide (NO) · in the development of the metastatic properties of nasopharyngeal carcinoma (NPC) is not fully understood. Previous studies proposed that interleukin-6 (IL-6) would act as regulator of matrix metalloprotease activation in NPC. Recently, we showed that (NO) · was a cri...

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Veröffentlicht in:	Tumor biology Jg. 37; H. 3; S. 3505 - 3514
Hauptverfasser:	Zergoun, Ahmed-Amine, Zebboudj, Abderezak, Sellam, Sarah Leila, Kariche, Nora, Djennaoui, Djamel, Ouraghi, Samir, Kerboua, Esma, Amir-Tidadini, Zine-Charaf, Chilla, Dalia, Asselah, Fatima, Touil-Boukoffa, Chafia, Merghoub, Taha, Bourouba, Mehdi
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Dordrecht Springer Netherlands 01.03.2016 Springer Nature B.V
Schlagworte:	Adult Biomedical and Life Sciences Biomedicine Cancer Research Carcinoma Head & neck cancer Humans Inflammation Interleukin-6 - physiology Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - metabolism Middle Aged Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms - enzymology Nasopharyngeal Neoplasms - mortality Nasopharyngeal Neoplasms - pathology Neoplasm Metastasis NF-kappa B - physiology Nitric oxide Nitric Oxide - physiology Nitric Oxide Synthase Type II - physiology Nitrites - metabolism Original Article Studies Nasopharyngeal carcinoma MMP Inflammation Nitric oxide IL-6
ISSN:	1010-4283, 1423-0380, 1423-0380
Online-Zugang:	Volltext
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