Neurosensory Prosthetics: An Integral Neuromodulation Part of Bioelectronic Device

Bioelectronic medicines (BEMs) constitute a branch of bioelectronic devices (BEDs), which are a class of therapeutics that combine neuroscience with molecular biology, immunology, and engineering technologies. Thus, BEMs are the culmination of thought processes of scientists of varied fields and her...

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Bibliographic Details
Published in:Frontiers in neuroscience Vol. 15; p. 671767
Main Authors: Ezeokafor, Ifeoma, Upadhya, Archana, Shetty, Saritha
Format: Journal Article
Language:English
Published: Lausanne Frontiers Research Foundation 16.11.2021
Frontiers Media S.A
Subjects:
auditory implants
Auditory pathways
bioelectronic devices
bioelectronic medicine
Biomedical materials
Carbon
Chronic illnesses
Deep brain stimulation
Diagnostic agents
Electrodes
Inflammation
Mimicry
Nervous system
Neural networks
Neuromodulation
Neurons
Neuroscience
Optic nerve
Photoreceptors
Physical properties
Prostheses
Prosthetics
Proteins
Quality of life
Retina
retinal implants
Sensory systems
Spinal nerves
Transplants & implants
Vagus nerve
vagus nerve stimulation
ISSN:1662-453X, 1662-4548, 1662-453X
Online Access:Get full text
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Summary:Bioelectronic medicines (BEMs) constitute a branch of bioelectronic devices (BEDs), which are a class of therapeutics that combine neuroscience with molecular biology, immunology, and engineering technologies. Thus, BEMs are the culmination of thought processes of scientists of varied fields and herald a new era in the treatment of chronic diseases. BEMs work on the principle of neuromodulation of nerve stimulation. Examples of BEMs based on neuromodulation are those that modify neural circuits through deep brain stimulation, vagal nerve stimulation, spinal nerve stimulation, and retinal and auditory implants. BEDs may also serve as diagnostic tools by mimicking human sensory systems. Two examples of in vitro BEDs used as diagnostic agents in biomedical applications based on in vivo neurosensory circuits are the bioelectronic nose and bioelectronic tongue. The review discusses the ever-growing application of BEDs to a wide variety of health conditions and practices to improve the quality of life.
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Reviewed by: Thordur Helgason, Reykjavík University, Iceland; Ignacio Delgado Martinez, Hospital del Mar Medical Research Institute (IMIM), Spain
This article was submitted to Neuroprosthetics, a section of the journal Frontiers in Neuroscience
Edited by: Winfried Mayr, Medical University of Vienna, Austria
ISSN:1662-453X
1662-4548
1662-453X
DOI:10.3389/fnins.2021.671767