Conservation of pyramidal tract in radiosurgery for brain metastases of lung adenocarcinoma: Three-dimensional analysis of biologically effective dose

Gamma knife surgery (GKS) for brain metastases (BMs) adjacent to the pyramidal tract (PT) is still a challenge to conduct. PT visualization and biologically effective dose (BED) calculation on a voxel-by-voxel basis may provide data to establish clinically safe values. We aimed to assess the relatio...

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Bibliographic Details
Published in:	Radiotherapy and oncology Vol. 179; p. 109451
Main Authors:	Tang, Ke, Zhang, Nan, Yuan, Xiaodong, Qian, Zenghui, Li, Yang, Feng, Xu
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier B.V 01.02.2023
Subjects:	Adenocarcinoma of Lung Biologically effective dose Brain metastases Brain Neoplasms - secondary Hematology, Oncology, and Palliative Medicine Humans Motor function Pyramidal tract Pyramidal Tracts Radiosurgery - methods Retrospective Studies Stereotactic radiosurgery Three-dimensional model Treatment Outcome BED Pyramidal tract PTCF PT MR CI Biologically effective dose VIFs BMs Brain metastases HR Three-dimensionalmodel IQR GKS Stereotactic radiosurgery CT 3D DTI Motor function magnetic resonance Gamma Knife surgery interquartile range three-dimensional model pyramidal tract conservation failure variance inflation factors motor function 3-dimensional computed tomography brain metastases stereotactic radiosurgery pyramidal tract hazard ratio biologically effective dose diffusion tensor imaging confidence interval
ISSN:	0167-8140, 1879-0887, 1879-0887
Online Access:	Get full text
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