Leonotis ocymifolia (Burm.f.) Iwarsson aerial parts aqueous extract mitigates cisplatin-induced nephrotoxicity via attenuation of inflammation, and DNA damage

Herein, we explored the protective effect of Leonotis ocymifolia (Burm.f.) Iwarsson aerial parts extract (LO) against cisplatin (CP)-induced nephrotoxicity in rats and profiled their phytocontents. A total of 31 compounds belonging to organic and phenolic acids and their glycosides as well as flavon...

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Bibliographic Details
Published in:	Frontiers in pharmacology Vol. 14; p. 1221486
Main Authors:	Mufti, Afoua, Feriani, Anouar, Ouchari, Wafae, Mandour, Yasmine M., Tlili, Nizar, Ibrahim, Mohammed Auwal, Mahmoud, Mona F., Sobeh, Mansour
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 01.08.2023
Subjects:	antioxidant DNA fragmentation Leonotis ocymifolia nephroprotective oxidative stress Pharmacology antioxidant nephroprotective Leonotis ocymifolia oxidative stress DNA fragmentation
ISSN:	1663-9812, 1663-9812
Online Access:	Get full text
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