Bilirubin as a potential causal factor in type 2 diabetes risk: a Mendelian randomization study

Circulating bilirubin, a natural antioxidant, is associated with decreased risk of type 2 diabetes (T2D), but the nature of the relationship remains unknown. We performed Mendelian randomization in a prospective cohort of 3,381 participants free of diabetes at baseline (age 28-75 years; women 52.6%)...

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Veröffentlicht in:	Diabetes (New York, N.Y.) Jg. 64; H. 4; S. 1459
Hauptverfasser:	Abbasi, Ali, Deetman, Petronella E, Corpeleijn, Eva, Gansevoort, Ron T, Gans, Rijk O B, Hillege, Hans L, van der Harst, Pim, Stolk, Ronald P, Navis, Gerjan, Alizadeh, Behrooz Z, Bakker, Stephan J L
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.04.2015
Schlagworte:	Adult Aged Alleles Bilirubin - blood Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - genetics Female Genetic Predisposition to Disease Genotype Glucuronosyltransferase - genetics Humans Male Mendelian Randomization Analysis Middle Aged Polymorphism, Single Nucleotide
ISSN:	1939-327X, 1939-327X
Online-Zugang:	Weitere Angaben
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