Custom human endogenous retroviruses dedicated microarray identifies self-induced HERV-W family elements reactivated in testicular cancer upon methylation control

Endogenous retroviruses (ERVs) are an inherited part of the eukaryotic genomes, and represent ~400 000 loci in the human genome. Human endogenous retroviruses (HERVs) can be divided into distinct families, composed of phylogenetically related but structurally heterogeneous elements. The majority of...

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Veröffentlicht in:	Nucleic acids research Jg. 38; H. 7; S. 2229 - 2246
Hauptverfasser:	Gimenez, Juliette, Montgiraud, Cécile, Pichon, Jean-Philippe, Bonnaud, Bertrand, Arsac, Maud, Ruel, Karine, Bouton, Olivier, Mallet, François
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Oxford University Press 01.04.2010
Schlagworte:	DNA DNA Methylation Endogenous Retroviruses - genetics Endogenous Retroviruses - metabolism Epigenesis, Genetic Gene Expression Profiling - methods gene overexpression Gene Regulation, Chromatin and Epigenetics Genetic Loci genome Humans inheritance (genetics) loci Male methylation microarray technology neoplasms Oligonucleotide Array Sequence Analysis - methods pathophysiology phylogeny placenta Retroviridae Retrovirus Reverse Transcriptase Polymerase Chain Reaction RNA Splicing Terminal Repeat Sequences testes Testicular Neoplasms - virology transcription (genetics) Transcription, Genetic transcriptome
ISSN:	0305-1048, 1362-4962, 1362-4962
Online-Zugang:	Volltext
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