High titre neutralizing antibodies in response to SARS–CoV–2 infection require RBD–specific CD4 T cells that include proliferative memory cells

Long-term immunity to SARS-CoV-2 infection, including neutralizing antibodies and T cell-mediated immunity, is required in a very large majority of the population in order to reduce ongoing disease burden. We have investigated the association between memory CD4 and CD8 T cells and levels of neutrali...

Full description

Saved in:

Bibliographic Details
Published in:	Frontiers in immunology Vol. 13; p. 1032911
Main Authors:	Phetsouphanh, Chansavath, Khoo, Weng Hua, Jackson, Katherine, Klemm, Vera, Howe, Annett, Aggarwal, Anupriya, Akerman, Anouschka, Milogiannakis, Vanessa, Stella, Alberto Ospina, Rouet, Romain, Schofield, Peter, Faulks, Megan L., Law, Hannah, Danwilai, Thidarat, Starr, Mitchell, Munier, C. Mee Ling, Christ, Daniel, Singh, Mandeep, Croucher, Peter I., Brilot-Turville, Fabienne, Turville, Stuart, Phan, Tri Giang, Dore, Gregory J., Darley, David, Cunningham, Philip, Matthews, Gail V., Kelleher, Anthony D., Zaunders, John J.
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 05.12.2022
Subjects:	Antibodies, Neutralizing CD4 function CD4 T cells CD4-Positive T-Lymphocytes COVID-19 Epitopes, T-Lymphocyte Humans Immunology neutralizing antibodies proliferation SARS-CoV-2 neutralizing antibodies SARS-CoV-2 CD4 T cells CD4 function proliferation
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!