Application of B cell immortalization for the isolation of antibodies and B cell clones from vaccine and infection settings

The isolation and characterization of neutralizing antibodies from infection and vaccine settings informs future vaccine design, and methodologies that streamline the isolation of antibodies and the generation of B cell clones are of great interest. Retroviral transduction to express Bcl-6 and Bcl-x...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 13; p. 1087018
Main Authors:	Boswell, Kristin L., Watkins, Timothy A., Cale, Evan M., Samsel, Jakob, Andrews, Sarah F., Ambrozak, David R., Driscoll, Jefferson I., Messina, Michael A., Narpala, Sandeep, Hopp, Christine S., Cagigi, Alberto, Casazza, Joseph P., Yamamoto, Takuya, Zhou, Tongqing, Schief, William R., Crompton, Peter D., Ledgerwood, Julie E., Connors, Mark, Gama, Lucio, Kwong, Peter D., McDermott, Adrian, Mascola, John R., Koup, Richard A.
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 13.12.2022
Subjects:	Antibodies, Neutralizing B cell B-Lymphocytes Cell Line chronic infection Clone Cells HIV Seropositivity HIV-1 Humans immortalization Immunology malaria vaccination Vaccines HIV-1 influenza B cell antibody chronic infection immortalization malaria vaccination
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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